Can Pets Be Trained to Detect Low Blood Sugar Episodes?

Pets—especially dogs—can indeed be trained to detect dangerous drops in blood sugar before you feel symptoms. Known as Diabetes Alert Dogs (DADs), these specially trained canines use their extraordinary sense of smell to identify chemical changes in your breath, sweat, or skin that occur when glucose levels swing out of range. While they’re not foolproof and should never replace medical devices, many provide valuable early warnings and emotional support for people living with diabetes.

Understanding How Dogs Detect Blood Sugar Changes

Dogs can detect volatile organic compounds (VOCs) in exhaled breath that change when blood glucose drops, particularly during hypoglycemia. Research shows that breath VOCs such as isoprene, acetone, and 2-butanone serve as biomarkers for hypoglycemia, though the analysis emphasizes using overall VOC patterns rather than individual compounds.

Exhaled breath isoprene rises significantly during hypoglycemia, showing a moderate negative correlation with blood glucose levels. When your blood sugar falls below normal, your body releases these chemical signatures at concentrations undetectable to humans but easily perceived by a dog’s highly developed olfactory system. DADs rely on their sense of smell to detect subtle changes in body odor caused by fluctuations in blood sugar, using their highly developed sense of smell to detect the scent that the body emits when blood sugar levels are off.

This scent-based detection often occurs 15 to 30 minutes before you notice typical warning signs like shakiness, dizziness, or confusion—giving you critical time to take corrective action.

The Science Behind Scent Detection

Canines can be trained to identify hypoglycemia simply and noninvasively by smelling exhaled volatile organic compounds. Machine learning models analyzing breath VOC patterns have achieved accuracy rates of 93%, with sensitivity of 92% and specificity of 95% in detecting hypoglycemia.

Statistical analysis of breath samples shows it is possible to detect hypoglycemia with sensitivity of 91% and specificity of 84% in controlled laboratory settings. However, real-world performance varies significantly. The chemical changes dogs detect are genuine biological phenomena, not anecdotal observations—they’re measurable, reproducible, and scientifically validated.

How Diabetes Alert Dogs Are Trained

Training a Diabetes Alert Dog is a rigorous, multi-stage process that typically takes 6 to 12 months. The estimated cost of breeding, raising, and training a dog that can recognize diabetic emergencies is around $35,000, though nonprofit agencies provide diabetic service dogs at low cost or even for free, with average waiting times of 2 to 5 years.

Scent Collection and Conditioning

The first step involves collecting scent samples during actual glycemic events. You’ll swab your sweat, saliva, or breath onto sterile materials when your blood sugar is low (typically below 70 mg/dL), normal (70–180 mg/dL), and high (above 180 mg/dL). These samples are stored and labeled for training purposes.

Training uses the same methods that the FBI and ATF use to train their scent detection working dogs, with dogs training at various times throughout the day, including nighttime alerts. During controlled sessions, dogs are exposed to labeled scent tubes and rewarded with treats, praise, or play when they correctly identify “low” samples. This positive reinforcement builds a strong association between the hypoglycemic scent and the reward.

Alert Behavior Development

Once dogs reliably recognize the scent, they learn to perform a specific alert behavior—such as nudging your hand, pawing at you, pressing a button, or bringing you a specific object. Some dogs are trained to press a button which sends an automated alert to five pre-determined phone numbers. Night training is the most important step, teaching dogs to remain alert for blood sugar levels while you are asleep and to wake you up in the event of an out-of-range BG level.

The alert must be deliberate, consistent, and unmistakable. Training progresses from controlled environments to real-world settings—home, car, grocery stores, and workplaces—to ensure the dog can perform reliably regardless of distractions.

Field Testing and Ongoing Reinforcement

When the client/trainer/dog team sustains the targeted level of alerts necessary for graduation, the team will be scheduled to graduate, and this will be repeated annually. Periodic refresh sessions and updated scent samples are essential to maintain accuracy over time. Dogs can lose their edge without consistent reinforcement, so ongoing training is a lifelong commitment.

Real-World Performance: What the Research Shows

While testimonials often describe Diabetes Alert Dogs as highly accurate, scientific studies reveal a more nuanced picture. When data was analyzed across participants, the overall accuracy rate was 54%, with a true positive rate of 69%. DAD accuracy was highly variable with 3/14 individual dogs performing statistically higher than chance.

One study of 27 DADs suggests that the accuracy of some dogs is very high, with a median sensitivity to hypoglycaemic episodes of 83%, which likely reflects the rigorous training and accreditation procedures of this well-established charity. However, accuracy ranging from 33% to 100% was observed, with Low BG Sensitivity averaging 59.1% and high variability across DADs.

Nighttime Detection Challenges

Sensitivity scores were lower during sleep hours of the person with diabetes (22.2% for low BG events and 8.4% for high BG events). This is particularly concerning since 55% of hypoglycemia episodes occur at night with most diabetics not waking up to the episode. Despite training specifically for nighttime alerts, many dogs struggle to maintain vigilance while their owners sleep.

Factors Affecting Accuracy

Most studies on the reliability and performance of diabetes alert dogs report potential lifesaving benefits but demonstrate notable variability and inconsistencies, which may be due to lack of required formal training or a certification process. Success relies not only on the quality of initial training, but also on post-accreditation factors such as placement environment, reward systems during working life, and each owner’s response to alerting behavior.

DAD accuracy is likely a complex process that can be affected by numerous factors, including the interactions between the DAD and its owner, and there are no regulatory guidelines for determining DAD accuracy. Individual dog temperament, owner compliance with reward protocols, environmental distractions, and the dog’s health all influence performance.

Diabetes Alert Dogs vs. Continuous Glucose Monitors

A study compared diabetes alert dogs against CGMs to determine which was more effective at detecting hypoglycemia, determining that CGMs were more accurate at detecting hypoglycemia than the dogs. About 70% of the time, the CGM was first to pick up the low BG, while dogs were first 19% of the time.

CGMs are generally more reliable and consistent compared to diabetic alert dogs, providing real-time glucose readings with high precision. CGMs offer continuous and accurate glucose monitoring, providing real-time information and alerts, and are more objective and do not require ongoing training or maintenance like DADs.

However, diabetic alert dogs offer a unique and reliable way to detect changes in blood sugar levels, especially during sleep or when CGMs might not be able to catch rapidly dropping glucose levels, and are particularly valuable at night. The known CGM lag time in monitoring glucose levels can pose a challenge to a rapid algorithm correction response, giving dogs a potential advantage in certain situations.

Complementary, Not Competitive

DADs should function as an important additional tool and component of a diabetes plan to facilitate tightened glycemic control, and should complement developing diabetes technology, rather than replace it. Results across all participants do not support the belief that DADs are more accurate than diabetes technology, but they offer benefits that technology cannot provide.

Service dogs provide more than alarm systems—aside from detecting lows, they give a companionship that is difficult to find anywhere else. Dogs can increase psychological and emotional functioning both from being trained to complete certain tasks and from acting as a companion.

Can Other Pets Help?

While dogs dominate the field of medical alert animals, there are anecdotal reports of cats displaying alert behaviors—such as persistent meowing, pawing, or unusual agitation—when their owners develop hypoglycemia. Case studies and surveys suggest that some pet dogs naturally respond to their owners’ hypoglycaemic state, and similar spontaneous responses have been observed in cats.

However, there are no formal cat training programs for diabetes detection. Cats lack the same trainability and work drive that makes dogs ideal for service tasks. Other animals, including rats, have been proven to be as good as—sometimes even better—than dogs when it comes to sniffing out diseases, but practical and social factors make dogs the most viable option for in-home medical alert work.

If your cat seems to react when your blood sugar drops, pay attention—but don’t rely on it as your primary detection method. Always confirm with a glucose meter or CGM.

What Alert Dogs Can and Cannot Do

What They Can Do

  • Detect hypoglycemia before symptoms appear: Many dogs alert 15–30 minutes before you feel symptoms, giving you time to treat the low.
  • Provide nighttime monitoring: Though accuracy drops during sleep, trained dogs can wake you during dangerous nighttime lows.
  • Retrieve emergency supplies: Dogs can fetch insulin from the fridge or help balance their partner when blood sugar levels are low.
  • Offer emotional support: Evidence supporting improved mental/physical health in persons using service dogs was robust.
  • Alert caregivers: Dogs can be trained to notify family members or press emergency buttons when you’re unable to respond.

What They Cannot Do

  • Replace medical devices: Diabetic alert dogs are animals prone to error and are not meant to replace your glucose monitor or any other medical device.
  • Guarantee 100% accuracy: Even the best-trained dogs miss alerts or produce false alarms.
  • Function without ongoing training: Performance degrades without consistent reinforcement and updated scent samples.
  • Work independently of owner involvement: You must actively participate in training, reward protocols, and daily care.
  • Detect all types of glucose changes: Rate of change analyses indicated that DADs were responding to absolute BG level, rather than rapid shifts in glucose levels.

Who Benefits Most from a Diabetes Alert Dog?

Ideal Candidates

People with hypoglycemia unawareness: HU occurs in approximately 40% of people with type 1 diabetes mellitus. The presence of HU increases the risk of severe hypoglycaemia six-fold for T1DM and 17-fold for T2DM. For these individuals, a dog’s external alert system can be lifesaving.

Those with frequent nighttime lows: If you experience dangerous drops while sleeping and your CGM alarms don’t wake you, a dog trained to physically rouse you can provide an additional safety layer.

People living alone: If you live by yourself, especially in rural or remote areas, a dog can summon help or alert emergency contacts when you’re unable to do so.

Individuals committed to ongoing training: Success requires active participation in scent collection, alert reinforcement, and daily interaction. If you’re willing to invest the time and effort, a DAD can be a valuable partner.

Children and their families: Hypoglycaemia unawareness is very common among children under the age of 6 years who are unable to observe the early symptoms of hypoglycemia by themselves, inducing a high risk of frequent and severe hypoglycaemia. Parents of young children with Type 1 diabetes often find DADs provide peace of mind and an extra layer of protection.

Who Should Reconsider

  • Those seeking a technology replacement: If you expect a dog to eliminate the need for glucose monitoring, you’ll be disappointed.
  • People with limited time or resources: Dogs require daily care, veterinary expenses, ongoing training, and significant financial investment.
  • Individuals with allergies or housing restrictions: Service dog protections exist, but practical barriers remain.
  • Those unwilling to accept variability: If you need 100% reliability, stick with medical devices.

Getting Started: Practical Steps

1. Choose a Reputable Program

Perusal of literature and Web-based resources found a range of available training, from formal (with certification) to do-it-yourself home training. Look for programs with proven track records, transparent success rates, and ongoing support. Organizations like Dogs4Diabetics maintain ethical and industry-leading standards for innovative scent-trained dogs, who can detect changes in blood sugar 20-30 minutes before the newest technology.

Ask about:

  • Training methodology and duration
  • Post-placement support and refresher courses
  • Success rates and client references
  • Certification standards and testing protocols
  • Costs, payment plans, and financial assistance options

2. Collect and Store Scent Samples

Whether you’re working with a professional trainer or training your own dog, you’ll need a variety of scent samples representing low, normal, and high glucose levels. Use sterile swabs or breath cards, label them clearly with your glucose reading and the date, and store them in airtight containers in the freezer.

The more samples you collect across different glucose ranges, the better your dog can learn to discriminate between normal and abnormal scents.

3. Use Positive Reinforcement Exclusively

Training uses positive reinforcement methods, focusing on rewarding good behavior and correcting unwanted behavior. Never punish a dog for missing an alert or producing a false alarm. Punishment erodes the dog’s confidence and willingness to alert, ultimately reducing accuracy.

Reward every correct alert immediately with high-value treats, enthusiastic praise, or play. Consistency is critical—every family member must follow the same protocol.

4. Set Realistic Accuracy Goals

Aim for at least 80% sensitivity (true positives) in controlled testing. Anything below 70% significantly reduces safety and may not justify the investment. Track your dog’s performance using a diary that records alerts, your glucose reading at the time of alert, and whether the alert was correct.

Work with your trainer to identify patterns—does your dog perform better at certain times of day? Are there specific glucose ranges where accuracy drops? Use this data to refine training.

5. Integrate with Your Existing Diabetes Management

Continue using your glucose meter or CGM as your primary monitoring tool. Treat your dog’s alerts as supplementary information that prompts you to check your glucose, not as a replacement for testing.

If your dog alerts and your CGM shows normal glucose, check with a fingerstick meter. Sometimes dogs detect changes before interstitial glucose (measured by CGM) reflects the drop in blood glucose.

6. Maintain Ongoing Training and Veterinary Care

Schedule regular refresher sessions with your trainer, update scent samples periodically, and ensure your dog receives routine veterinary care. A sick or stressed dog cannot perform reliably.

Monitor your dog for signs of burnout—decreased enthusiasm for alerts, reluctance to work, or behavioral changes. Just like human workers, dogs need breaks, vacations, and mental health support.

Understanding the Costs

The financial investment in a Diabetes Alert Dog is substantial. The estimated cost of breeding, raising, and training a dog that can recognize diabetic emergencies is around $35,000. This typically includes:

  • Initial breeding and puppy raising
  • 6–12 months of professional training
  • Placement and orientation with your family
  • Initial supplies and equipment

Ongoing costs include:

  • Food, treats, and supplements: $50–$100/month
  • Veterinary care: $500–$1,500/year
  • Refresher training sessions: $200–$500/year
  • Replacement gear and supplies: $200–$400/year

Nonprofit agencies provide diabetic service dogs at low cost or even for free, but their waiting lists tend to be long, with average waiting time of 2 to 5 years. Some organizations offer payment plans or financial assistance based on need.

Insurance rarely covers the cost of a Diabetes Alert Dog, though you may be able to deduct expenses as medical costs on your taxes. Consult a tax professional for guidance.

The Americans With Disabilities Act considers your Diabetic Alert Dog a service dog, which means you have the right to be accompanied by your dog in public places, housing, and on airplanes (with proper documentation).

However, you must ensure your dog is well-behaved, under control, and performing trained tasks related to your disability. Businesses can ask two questions: (1) Is the dog a service animal required because of a disability? (2) What work or task has the dog been trained to perform? They cannot ask about your specific disability or demand documentation, though airlines have different rules.

Your dog must be housebroken, non-aggressive, and not disruptive. If your dog misbehaves, businesses have the right to ask you to remove the animal.

The Emotional and Psychological Benefits

Beyond glucose detection, Diabetes Alert Dogs provide profound emotional support. Evidence supporting improved mental/physical health in persons using service dogs was robust. Living with diabetes—especially Type 1—involves constant vigilance, fear of hypoglycemia, and anxiety about complications.

Dogs can increase psychological and emotional functioning both from being trained to complete certain tasks and from acting as a companion. They offer:

  • Reduced anxiety: Knowing your dog is monitoring your glucose can ease fear of nighttime lows or hypoglycemia unawareness.
  • Increased independence: Children and adults with DADs often feel more confident engaging in activities without constant caregiver supervision.
  • Non-judgmental support: Dogs can act as nonjudgmental supporters, sitting or walking by your side as you tackle the huge journey of living with a chronic illness.
  • Social connection: Service dogs often spark conversations and connections with others, reducing isolation.

For many families, these intangible benefits justify the investment even when accuracy isn’t perfect.

Limitations and Realistic Expectations

It’s essential to approach Diabetes Alert Dogs with realistic expectations. In this study the majority of DADs did not demonstrate accurate detection of low and high BG events, however, performance varied greatly across DADs. There is a sizeable gap between the picture of DAD accuracy that has emerged from the majority of recent scientific studies compared to the reports of people with diabetes who own and use DADs.

This discrepancy likely reflects several factors:

  • Selection bias: People who have positive experiences are more likely to share testimonials.
  • Subjective interpretation: Owners may remember successful alerts more vividly than missed ones.
  • Variability in training quality: Not all programs produce equally reliable dogs.
  • Individual dog differences: Some dogs are naturally more talented at scent work than others.

This was a very small study, so it was too small of a sample size to draw any real conclusions, and since there isn’t just one standard for training DADs, we may not be getting the full picture of the effectiveness of the dogs as a group.

The Future of Diabetes Alert Technology

While Diabetes Alert Dogs remain valuable for many people, technology continues to advance. RealNose secured just over $1 million in venture capital funding in early 2024 to build a prototype that develops a unique platform capable of identifying scent signatures, creating an AI-driven electronic device that mimics canine olfaction.

These developments may eventually provide the benefits of canine scent detection without the care requirements, costs, and variability of living animals. However, for thousands of people around the world who are partnered with a medical detection dog, what researchers call the “dog packaging” is just as important as the technology, and the additional comfort, security and companionship that a medical detection dog brings may never be replaced by technology.

While CGM and AID systems help mitigate issues, they are not foolproof. IAH is highly prevalent and related to a higher risk for severe hypoglycemia in T1D patients using CGM, suggesting that even with advanced technology, some people still need additional layers of protection.

Making the Decision

Deciding whether to pursue a Diabetes Alert Dog is deeply personal. Consider these questions:

  • Do you experience hypoglycemia unawareness or frequent severe lows despite using a CGM?
  • Are you willing to invest significant time, money, and effort in training and care?
  • Do you have the living situation, lifestyle, and family support to accommodate a service dog?
  • Are you comfortable with the variability in performance and the need for ongoing training?
  • Would the emotional and psychological benefits justify the investment even if accuracy isn’t perfect?

If you answered yes to most of these questions, a Diabetes Alert Dog might be a valuable addition to your diabetes management team. If you’re seeking a technology replacement or guaranteed accuracy, focus on optimizing your CGM and insulin delivery system instead.

Bottom Line

Yes—dogs can truly be trained to detect drops in blood sugar before symptoms appear, offering valuable early warning and emotional reassurance. Canines have the capability to detect numerous medical conditions, including dangerous fluctuations in blood sugar in persons with diabetes, especially hypoglycemia.

However, they are partners, not medical devices. Results do not support the belief that DADs are more accurate than diabetes technology, but they offer benefits that technology cannot replicate. Success depends on sound training, your active involvement, and continued use of standard glucose monitoring tools.

For many people—especially those with hypoglycemia unawareness, frequent nighttime lows, or limited access to advanced technology—a well-trained alert dog can be a lifesaver. But only when integrated responsibly into a comprehensive care plan that includes regular glucose monitoring, appropriate insulin management, and ongoing medical supervision.

The decision to pursue a Diabetes Alert Dog should be made in consultation with your endocrinologist, diabetes educator, and family. Weigh the costs, benefits, and limitations carefully. If you proceed, choose a reputable training program, commit to ongoing reinforcement, and maintain realistic expectations.

Your dog can be a loyal companion and valuable safety net—but never your only line of defense against dangerous blood sugar swings.

For more information on diabetes management and glucose monitoring technologies, visit the American Diabetes Association, JDRF, CDC Diabetes Resources, National Institute of Diabetes and Digestive and Kidney Diseases, and Assistance Dogs International.